A Secret Weapon For ceesdekker.net

A Secret Weapon For ceesdekker.net

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Employing single-molecule optical and AFM imaging and force-spectroscopy procedures, we search for to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our investigate pursuits incorporate:

Human Rad51 filaments on double- and one-stranded DNA: correlating normal and irregular varieties with recombination function.

Multicolor imaging on the bacterial nucleoid and cell division proteins with blue, orange, and near-infrared fluorescent proteins

Considering that 2000, Dekker has shifted the main target of his get the job done towards biophysics the place he experiments the properties of solitary biomolecules and cells utilizing the applications of nanotechnology. This change of discipline was pushed by his fascination for that remarkable working of biological molecular buildings, along with with the extensive-term perspective that lots of exciting discoveries is usually expected Within this area.[5] Existing traces of exploration in his biophysics group are from the parts of:[six]

2015, discovery that condensin is a really versatile protein structure; and to start with detection of DNA knots working with nanopores

Instance (3) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim with the pore is highlighted in crimson, and a 3D rendering of your motion of the DNA rod is exhibited.

We form germs into types that deviate from their all-natural phenotype. Particularly, I'll clearly show our capacity to form Reside E. coli bacteria into novel styles for instance rectangles, squares, triangles and circles.

Move-driven rotary motors like windmills and drinking water wheels push purposeful procedures in human society. Though examples of these rotary motors also aspect prominently in mobile biology, their synthetic construction in the nanoscale has remained demanding. Below we demonstrate flow-driven rotary motion of a self-organized DNA nanostructure that's docked onto a nanopore in a thin reliable-point out membrane. An elastic DNA bundle self-assembles right into a chiral conformation on phoretic docking on to the stable-point out nanopore, and subsequently shows a sustained unidirectional rotary movement of up to twenty rev s−1.

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It had been through this era that Dekker performed research on magnetic spin methods and on sound in superconductors and semiconductors.

In 1993 he was appointed as Associate Professor at Delft College of Technology. Inside the mid-nineteen nineties Dekker and his team reached success with the discovery on the Digital Attributes of carbon nanotubes, the initial solitary-molecule transistor and various nanoscience.

1999, to start with measurement ceesdekker.net on the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for your new Luttinger description of interacting electrons in nanotubes

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‘I am driven by surprise and inquiries. On a cloth stage I obtain responses in physics, but I encounter my deepest joy with God. That faith also drives my science And just how I manage individuals.